The club's home opener will be on Friday, April 5 against the Minnesota Twins.
The team's interleague schedule includes games against the National League West. The Orioles will host the Dodgers on April 19-21, the Padres on May 14-15 and the Rockies on August 16-18. They will also make an August West Coast road trip to San Diego, San Francisco and Arizona.
The Orioles continue their home-and-home series against the neighboring Nationals. They will play two games at Washington on May 27-28 and then host the Nats the next two days on May 29-30.
The O's will have 16 home games in June, the most of any month, and will play 49 of their 96 games before the All-Star break at home. They will have two nine-game homestands, including one from April 16-24 against the Rays, Dodgers and Blue Jays.
After that, they will take an 11-game road trip, going to Oakland, Seattle and Los Angeles (Angels) from April 25-May 5.
The Houston Astros, who will be joining the American League next season, will come to Camden Yards on July 30-August 1. The Orioles visit Houston on June 4-6.
Game times will be announced at a later date.
Here's the complete schedule.