Hopkins was informed of the decision Monday and immediately relieved of his duties. Orioles amateur scouting director Gary Rajsich said he made the decision, citing philosophical differences.
The timing, just a few days after baseball's annual amateur draft, will allow Hopkins plenty of time to catch on with another club while the Orioles look to fill the position sometime later this summer, Rajsich said.
"We will interview some candidates in-house and some guys out-of-house," Rajsich said. "But we won't do that immediately -- that will be more towards the end of the summer."
Hopkins, who did not return an immediate phone call seeking comment, joined the Orioles in 2011 after spending seven years with the Texas Rangers. He was considered a potential candidate for the Orioles scouting director position before new executive vice president Dan Duquette hired Rajsich in November. He served as the Orioles' informal acting scouting director in the period between Joe Jordan leaving for the Philadelphia Phillies in October and Rajsich's hiring in November.
As a national crosschecker, it was Hopkins' responsibility to follow up on area scouts' opinions of players for the amateur draft, which concluded last Wednesday.
While the Rangers' scouting director, he drafted several players currently with the Orioles' organization, including Chris Davis, Tommy Hunter, Zach Phillips and Taylor Teagarden.