Enes Kanter had 20 points and 10 rebounds and Serge Ibaka added 15 points and eight rebounds for Oklahoma City, which won its seventh straight.
The game also had little effect on the standings: San Antonio is likely to finish second in the Western Conference and the Thunder are virtually locked into third. But the Thunder said it was important to maintain momentum.
David West and Jonathon Simmons each scored 17 points for the Spurs.
Cleveland 107, at New York 93: LeBron James had 27 points, 11 rebounds and 10 assists in his third triple-double of the season, Kevin Love added 28 points and 12 rebounds, and the Cavaliers beat the Knicks.
Atlanta 112, at Detroit 95: Paul Millsap had 23 points and nine rebounds, and the Hawks snapped the Pistons' five-game winning streak. The Hawks have won 13 of their last 16 and moved a game ahead of Miami atop the Southeast Division.
at Orlando 111, Chicago 89: Orlando journeyman center Dewayne Dedmon scored a career-high 18 points and grabbed 13 rebounds, Jason Smith added 14 off the bench and the Magic dealt the Bulls a blow to their fading playoff hopes.
Toronto 115, at New Orleans 91: DeMar DeRozan scored 23 points, Patrick Patterson had 16 and the Raptors snapped a two-game losing streak, beating the Pelicans to tie a franchise record with their 49th victory of the season.
Charlotte 115, at Milwaukee 91: Nicolas Batum scored 23 of his 25 points in the first half and the Hornets used a three-point barrage to rout the Bucks. Marvin Williams added 21 points and Kemba Walker had 18 for the Hornets, who took three of four games in the season series.
Utah 93, at Minnesota 84: Gordon Hayward scored 16 of his 18 points in the fourth quarter and the road-weary Jazz finished a five-game trip with a victory over the Timberwolves.
Boston at Phoenix: Late.
Philadelphia at Portland: Late.