It started well enough for the Jayhawks, but after a 10-0 lead in the first quarter, the wheels came off quickly.
Texas Tech scored 20 points in the second quarter to take a 20-10 halftime lead, and then scored 34 more before the Jayhawks finally found the end zone with just under 8 minutes to play in the game, but it was too little, too late, as the No. 20 Red Raiders won 54-16.
Jake Heaps led the 'Hawks with 189 yards passing on 16 of 32 attempts, with 1 touchdown and 1 interception.
Darrian Miller had 12 carries for 59 yards, but the backfield that is considered by many as the best in the Big 12 had only 85 yards total.
Tony Pierson finished with six receptions for 118 yards.
For Texas Tech, it was all about the passing as quarterback Baker Mayfield, a true freshman walk-on passed for 368 yards before leaving the game with an apparent leg injury in the third quarter. Mayfield finished 32 of 51 with an interception.
First year head coach Kliff Kingsbury now has the Red Raiders at 5-0 for the first time since 2008. For the Jayhawks, they will have to wait another week for the elusive Big 12 win they've been seeking, with this being the 22nd straight Big 12 loss.
Texas Tech will next face Iowa State on October 12, while the 2-3 Jayhawks will travel to TCU.