Jazimen Gordon and Haleigh Lankster each scored 16 points to lead WSU and Lankster finished with a double-double as she pulled down a game-high ten rebounds.
Jessica Diamond added 15 points and the junior guard has now scored in doubles figures in eight-straight games, and 18 of WSU's 20 games this season.
Chynna Turner was the other player in doubles figures as she had 10 points to go along with seven rebounds.
ISU's Brittany Schoen finished with a game-high 20 points on her way to passing the 1,000 career point mark. The senior guard knocked down five three pointers and helped keep the Sycamores close at the end of the game.
Anna Munn was the only other Sycamore in double figures with 11 points.
WSU used a 10-0 run with eight points from Gordon to open the second half but Indiana State answered with a 14-4 run to take a 50-49 lead after Munn hit a layup.
Diamond and Lankster hit back-to-back layups to push the WSU lead to 53-50 but Schoen tied the game with a long three-pointer. Gordon's layup and a jumper by Alicia Sanchez extended the Shockers lead to 57-53 but a trey by Schoen cut the Shockers lead to one with 5:29 left in the game.
Another jumper by Sanchez and a Lankster free throw pushed the Shockers lead back to four at 60-56. Schoen was fouled on a three-attempt and knocked down all three free throws to cut the lead to one once again going into the final media timeout of the game.
Turner hit a layup out of the timeout to extend the Shockers lead to 62-59 and Shannon Thomas hit one of two free throws to make the score 62-60 with 3:18 left in the game. WSU would go on a 14-3 run to close the game to give them the victory.
Down by as much as ten points in the first half, the Shockers stormed back over the final four minutes with a 10-2 run to take a 36-35 halftime lead. Turner and Lankster each scored four points in the run.
After today, WSU will start a three-game road trip, which starts with a trip to play the Creighton Bluejays this Thursday, Feb. 2 followed by a trip to Des Moines to face the Drake Bulldogs on Saturday, Feb. 4.
The Shockers will than travel to Springfield, Mo. to face Missouri State on Friday, Feb. 10 and the game will start at 7 p.m. and can be seen on MVC-TV. They will return to Charles Koch Arena on Friday, Feb. 17 to host Southern Illinois.
WSU remains in first place in the MVC, two games ahead of Missouri State and UNI, who both won on Sunday.