The Philadelphia Phillies won the opening game of the World Series 6-1 over the host New York Yankees on Wednesday behind the masterful pitching of Cliff Lee and two home runs by Chase Utley.

Lee baffled the Yankees with an assortment of fastballs, changeups and curves, limiting them to six hits, striking out 10 and inducing a string of weak swings and easy outs.

An unearned run in the bottom of the ninth was the only blemish on his Lee's pitching line as he humbled the American League champions and erased their home field advantage in the series.

Utley hit a high fly off Yankees starter CC Sabathia that just cleared the right-field fence for a homer with two outs in the third inning, and crushed an 0-2 fastball into the second deck of bleachers in right-center in the sixth.

The Phillies, who won last year's World Series, tacked on two insurance runs in the eighth and two more in the ninth off Yankees relievers.

Game Two of the best-of-seven series will be in New York on Thursday with the Phillies starting Pedro Martinez against A.J. Burnett of the Yankees.