The Indianapolis Colts will look to make it five straight wins over the Broncos when the two teams get together Sunday at Invesco Field at Mile High. Indy will be a bit short handed, however. Wide receiver Pierre Garcon and linebacker Clint Session were both left behind due to injury.

The Colts still have Peyton Manning though, and plenty of other weapons on offense. Last week, against the Giants, Indianapolis also discovered a running game. Joseph Addai and Donald Brown combined for more than 160 yards rushing. That kind of success on the ground opens up the field and makes Manning even more dangerous.

Denver is home for the second straight week after knocking off Seattle 31-14 last Sunday. Leading rusher Knowshown Moreno will not play against Indy, however. That puts more pressure on quarterback Kyle Orton. The veteran out of Purdue has a passer rating of 103.9 through two games and has thrown just one interception. The Broncos line will need to keep him upright against the bookend Colts pass rushers Dwight Freeney and Robert Mathis who each tallied two sacks against New York.

The game will played under the cloud of sorrow for Denver. Earlier in the week, Broncos wide receiver Kenny McKinley was found dead of an apparent self-inflicted gun shot wound. The South Carolina product was placed on injured reserve after knee surgery last month. McKinley was 23 years old.

Kickoff Sunday is set for 4:15pm Indianapolis time.