It was Norfolk State's fourth straight win over Virginia State (1-1).
Virginia State, a Division II program, took a 3-0 lead in the first quarter on a 42-yard field goal by Justin Parker. Norfolk State answered with four straight touchdowns for a 28-3 lead. Norfolk's other scores came on a touchdown pass from Dennis Brown to P.J. Hayden and a 13-yard run by former Hampton High player Cotton Donovan. Donovan ended his night with six carries for 37 yards.
Sherron Childress of Hampton added three receptions for the Spartans.
The Norfolk State defense dominated, allowing only 169 total yards and 12 first downs. Norfolk State intercepted three passes and recovered two fumbles.
Florida A&M 21, Delaware St. 12Curtis Pulley rushed for 196 yards to lead Florida A&M to a win over visiting Delaware State.
The Rattlers (1-0, 1-0 MEAC) rushed for 328 yards as a team and snapped a four-game losing streak to the Hornets (0-1, 0-1).
It was the Rattlers' second straight season-opening win.
Pulley had FAMU's longest run, a 47-yard touchdown jaunt, dancing around several defenders at midfield, before breaking free and racing down the sideline to give the Rattlers a 21-6 lead in the third quarter.
Pulley also was 12 of 19 for 140 yards.
Delaware State quarterback Anthony Glaud, making his first start, was 17 of 32 for 188 yards and a first-half touchdown.
FAMU's Lonvontae Page added 61 yards and a touchdown on 20 carries, and Mykel Benson had a 1-yard touchdown run.
N.C. A&T 19, Winston-Salem St. 10Mike Mayhew's 5-yard touchdown run capped a nine-point fourth quarter in North Carolina A&T's road win over Winston-Salem State.
The Aggies, who led 13-10 after a field goal by Patrick Courtney in the third quarter, secured the game following a Winston-Salem State fumble.
Brandon Young recovered the fumble by Winston-Salem State quarterback Branden Williams on the Rams' 18-yard line with 4:14 left in the game.
Mayhew scored after Carlton Fears rushed for 17 yards on two carries.
Fears had 131 passing yards and 78 rushing yards and one touchdown.
The Rams, who fumbled the ball twice for turnovers, had just 33 rushing yards in the game.
Williams threw for 42 yards, but lost 20 on the ground. Jarrett Dunston had the Rams' lone touchdown on a 1-yard run in the second quarter.
Shaw 20, Bethune-Cookman 6Travis Robinson threw for a touchdown and Raymond Williams ran for another as Shaw beat Bethune-Cookman in Daytona Beach, Fla.
Robinson was 3-of-11 passing for 91 yards and an interception for the Bears (2-0), and Williams rushed for 69 yards.
Shaw's defense constantly stymied Bethune-Cookman and forced seven turnovers, forcing two fumbles inside the Shaw 10-yard line.
A 16-yard run by Williams early in the second quarter provided Division II Shaw a 17-0 lead, and the Bears made it 20-0 at 3:03 of the third quarter on Caleb Reid's 23-yard field goal.
The Wildcats (0-1), a Football Championship Subdivision team, scored their only points with 13:31 remaining on a 12-yard run by Brian Sumlar.
It was only the second meeting between the schools.