After dropping a 76-59 decision at Binghamton on Friday, the Bears flew to Tampa, Fla., and took charge early, building 32-26 advantage by halftime.
Phillip Carr and Martez Cameron each contributed 10 points and Tyjhai Byers had nine rebounds as Morgan State handed the Bulls their first loss after giving first-year head coach Brian Gregory a win in his debut when Stephan Jiggets hit a jumper with 12 seconds left to beat Florida Atlantic.
Morgan State hit 20 of 50 from the field (40 percent) and made five of 12 from beyond the arc. South Florida got 13 points from Terrence Samuel, a graduate transfer from Penn State, and 11 from Tulio Da Silva while shooting 34.8 percent from the field (16 of 46), including four of 16 from deep.
Towson 89, Frostburg State 45: Deshaun Morman scored 19 points and Jordan McNeil (Mount Saint Joseph) had 17, both career highs, and the Tigers rolled over the Division III Bobcats.
Morman made eight of 10 shots and McNeil six of nine, including four of seven from 3-point range. Zane Martin and another reserve, Justin Gorham, had 10 points for the Tigers (1-1).
Tyler Michael had 10 points for the Bobcats. Frostburg State shot just 26.2 percent, including 1-for-16 from 3-point range.
Towson was permitted to schedule the game as part of the NCAA's exempted Gulf Coast Showcase, in which the Tigers will head to Estero, Fla., for three games next week.
The Tigers had a 53-33 rebounding advantage with Gorham grabbing nine.
No. 13 Notre Dame 88, Mount St. Mary's 62: Bonzie Colson had 27 points, 11 rebounds and three blocks, and the Fighting Irish shook off a choppy opening half to roll past the Mountaineers in their home opener.
It was the 25th career double double of his career. Rex Pflueger added his first with 14 points and 10 rebounds.
Matt Farrell chipped in 12 points and five assists as the Irish improved to 18-0 in home debuts under coach Mike Brey.
Colson, an Associated Press preseason All-American, went 11-of-15 from the field and 4-of-4 at the foul line.
Junior Robinson, the Mountaineers' 5-foot-5 senior guard, led the visitors with 14 points but had just two after halftime. Freshman Bobby Planutis added 11 points and seven boards.
The Irish led just 40-32 at the half but scored the first 14 points of the second half to seize control.
Morgan State 123, Cheyney (Pa.) 53: Braennan Farrar scored 25 points and Tykyrah Williams added 24 to lead the host Bears (1-1) over the Division II Wolves (0-3).
Morgan State shot 71 percent from the field, including 75 percent (12-for-16) from 3-point range while holding Cheyney to 35.8 percent shooting.
Tayler Miller scored 13 points and Lexus Spears and Jihayah Chavis each added 12 for the Bears.
Octavia Hawkins was the only Wolves player to score in double figures, with 13 points.
Buffalo 76, UMES 41: Summer Hemphill scored 12 points off the bench to lead the host Bulls (2-0) over the Hawks (1-1).
Amanda Carney scored 11 points off the bench and Alexus added 10 for UMES, which was held to 22.2 percent shooting from the field.