Jennifer Aniston, Miley Cyrus, Melissa McCarthy, Dave Grohl, Sandra Bullock, 50 Cent and Gwen Stefani were among the many celebrities who gathered to send off late night host Chelsea Handler on her final E! talk show.
Handler, who is moving to Netflix, was also joined by Selena Gomez, Gerard Butler, Wiz Khalifa, Chloe Moretz, Johnny Knoxville and Fergie, among a slew of other stars, for their "We Are the World"-esque performance of "Roll Yourself a Joint and Have a Drink."
"I'm really really appreciative to E! for giving me this opportunity to do the show and I never really got a chance to be serious and say thank you," she told the audience.
"I'll see you on Netflix!"
Earlier in the show, Bullock and Aniston staged an intervention for the late night host alongside another friend Mary McCormack.
The trio joked that Handler's move to Netflix was code for rehab.
"Netflix is a wonderful facility where you'll be able to get all the help you need," they told her.
Cyrus performed a version of Roy Orbison's "It's Over" as well while Ellen DeGeneres appeared in a "Nude Shower Fight" segment.
Later, Handler was surprised by former lover, rapper 50 Cent, who also performed for the live audience.
"I did end our relationship abruptly," she admitted to the the rapper. "I wanted you to know I have not dated a black man since."
"They say when you go black you can't go back well I came running back."
Related storiesVideo Music Awards 2014: Winners ListSandra Bullock and David Gordon Green Team on 'Our Brand is Crisis' (EXCLUSIVE)Netflix Adds Bill Cosby Stand-Up Special to Comedy Lineup 2014 Variety Media, LLC, a subsidiary of Penske Business Media; Distributed by Tribune Content Agency, LLCCopyright © 2014, The Baltimore Sun