Become a digitalPLUS subscriber. 99¢ for 4 weeks.

WATCH: Mark Ruffalo's Voice Is a Cure in 'The Normal Heart' Trailer

Mark RuffaloBilly CrystalOff-Broadway TheaterJustin TherouxRyan MurphyTaylor Kitsch

The promos for Ryan Murphy's HBO drama keeping getting more and more powerful.

The first full trailer shows Mark Ruffalo, his onscreen partner Matt Bomer and Julia Roberts fight to raise awareness about the AIDS epidemic in New York City in the early 1980s. The pic follows gay activists and the medical community as they try to expose the truth about the crisis. At one point, Ruffalo's character accuses the government of a conspiracy to murder all gay men.

"To win a war, you have to start one," Ruffalo says in the clip.

Larry Kramer himself scripted the TV adaptation of his hit 1985 Tony-winning off-Broadway play. The HBO movie, which also star Taylor Kitsch, Jim Parsons and Alfred Molina, will air on May 25. Jonathan Groff, the star of another HBO program, "Looking," also makes an appearance in the telefilm.

HBO is already eyeing a sequel that would follow Ruffalo's Ned Weeks through the 1990s as he tries to help those dying from the disease.

Related storiesTV Review: Billy Crystal's '700 Sundays'WATCH: Justin Theroux Searches for Answers in HBO's 'The Leftovers' Teaser'Game of Thrones' Puts Its Own Spin on Happily Ever After (SPOILERS) 2014 Variety Media, LLC, a subsidiary of Penske Business Media; Distributed by Tribune Content Agency, LLC

Copyright © 2014, The Baltimore Sun