RBs C.J. Spiller (745 yards, 4.6 ypc, 2 TDs) and Fred Jackson (725 yards, 4.2 ypc, 7 TDs) are a tough duo. They'll get lots of work, as usual. Buffalo is fourth in rushing at 138.2 yards per game. The Dolphins have to choke off the running game and put things on the shoulders of young QB Thad Lewis. The Dolphins are 22nd in rush defense at 117.2 yards per game. The Dolphins front seven will be under a lot of pressure.
Tom Szczerbowski / Getty Images