The Knights (24-6 overall, 5-1 in C-USA) are ranked No. 15 in the latest Baseball America poll and are alone in first place in the C-USA standings.
UAB is 18-12 overall and 2-4 in C-USA play.
If UCF can pull off a sweep of the Blazers, the Knights have a shot at entering the Top 10 in the Top 25 polls.
UCF has relied on a mix of steady pitching and timely hitting so far this season.
Junior first baseman D.J. Hicks has emerged as the team's ace hitter. He is tied for the national lead with 43 RBI so far this season.
UCF's pitching staff, which is loaded with especially strong relievers, currently boasts a 2.90 ERA through 270 innings this season.
The Knights are slated to take on the Blazers Friday at 6:30 p.m., Saturday at 4 p.m. and Sunday at 11 a.m.
On Friday, the first 300 fans in attendance will receive a free T-shirt.
UCF is hosting an Easter egg hunt at 3 p.m. Saturday, an hour before the Knights' game. Children ages 3-12 can participate in the egg hunt and will receive a free ticket to the game.
UCF coach Terry Rooney said a strong home crowd can give the Knights a big boost.
"We want UCF to be Orlando's baseball team," he said. "We really do. ... I think once you come out here and see what we have, the product that we have. We've got a Top 20 baseball team here right now. Our guys are playing great, and I think we're ranked as high as 14th in the country.
"I say those things, there's a long way to go, but I say those things [because] I want people in Central Florida to understand that you've got one of the best baseball teams in the country. These kids are playing great, obviously the facility's been improved -- and it certainly helps, there's no question. We've had some great crowds and we've got a very good UAB team coming in, so hopefully everybody in the Orlando community will come out."