Perhaps familiarity would finally lead to victory.
When your a team desperate for a win, any foreseen advantage is considered.
But some optimism could be gathered for the Colts as they looked towards their 14th attempt to break into the left column of the standings in 2011. Ahead of them are the Tennessee Titans, an opponent who they'll see for the second time this season.
Its one of three remaining games against divisional teams to whom the Colts have history and knowledge. Last season, three wins over divisional opponents in their second time around got the team into the playoffs.
Indeed, the second time was the charm to bring the first.
The Colts outscored the Titans 24-7 in the second half to pick up a 27-13 victory, their first on the year. It avoids the worst start in franchise history and prevent the Colts from becoming the second team in league history to lose 16 games.
Optimism was indeed among the nearly full Lucas Oil Stadium in the first quarter, when the Colts defense, shutdown the Tennessee offense and holding them off the scoreboard. Adam Vinatieri booted a 47-yard field goal to make it 3-0.
Fate dealt the Colts' defense a bad hand in the second quarter, as a bad punt led to a short Tennessee drive and a 52-yard field goal by Rob Bironas to tie the score. Late in the quarter, Pierre Garcon fumbled after a 17-yard reception, giving the ball to the Titans in Colts territory.
Matt Hasselbeck then drove Tennessee deep into Colts territory to set up another Bironas field goal to make it 6-3.
But the second half belonged to the Colts. Reggie Wayne caught an 18-yard touchdown pass in the third quarter to give the Colts the lead at 10-6. Jacob Lacey helped extend the lead later on when he picked off a Hasselbeck pass and took it 32-yards for the score to make it 17-6.
Tennessee turned to Jake Locker in the fourth quarter and he brough the Titans back as he threw a touchdown pass to Nate Washington to make it 17-13. But Donald Brown sealed the game soon after with a tackle-breaking 80-yard touchdown that put the game away.