Moore, 38, is a well-respected African-American writer, Army veteran and Rhodes Scholar who runs a company called BridgeEdU that helps universities improve graduation rates by mentoring freshman students.
He rose to fame with his 2010 book, "The Other Wes Moore," which chronicled his life and that of another boy by the same name who was born a block away in Baltimore but traveled a much different path.
Moore recently produced a PBS documentary called "All the Difference" about two young African-American men from inner-city Chicago becoming the first in their families to attend college.
If approved by the Maryland Senate, Moore would join the Board of Regents that sets policy and tuition for the 12 institutions comprising the state university system.
Moore's nomination was one of 189 so-called "green bag" appointments presented to the Senate on Friday. By tradition, the appointments are delivered in a green satchel.