But Fisher injured her leg in the fist 30 seconds of the game and the Comets capitalized by taking a 6-0 lead with all the points coming in the paint.
Barton (6 rebounds) scored the first basket and McDonald (7 points, 5 rebounds) scored the next two field goals.
Fisher returned with 3:52 left in the period, but the Comets had stretched the lead to eight points and the Indians (16-5) never got any closer.
Catonsville outrebounded the Indians 42-25 and forced 31 turnovers.
The Comets only shot 32 percent from the field (21-for-66), but they held the Indians to just 27 percent (11-for-41) and scoreless from beyond the three-point arc (0-for-14).
“Offensively, we just weren’t there,” Franklin coach Denikwa James said.
Gast was the only Comet who scored in double figures, but they also got eight points from her younger sister, Jennifer Gast, six points from McTaggart and four each from Barton, Breya Wallace and Maja Wichhart.
Wallace led the team with five steals, but Barton and Renee Gast had four each and McTaggart and McDonald had three each as the Comets finished with 21 steals.
Gast admitted her intensity was up because of Franklin’s lofty record.
“I was expecting a harder game tonight,” she said. “I wished it would have been a harder game because I think the good competition would help us against Milford on Tuesday.”
Franklin coach James admitted her squad’s 52-47 victory over Chesapeake on Wednesday took its toll.
“It was a very tough win and they were very aggressive, a very good team so I think we were a little tired mentally,” she said. “You can’t be tired mentally, because they (Catonsville) definitely pressed fullcourt.”
Mohler hopes the Comets can match the intensity and quickness of Milford Mill (17-1).
“One of our goals was to get to the county championship,” Mohler said. “Our next goal is to try and win it and then try and win the region.”