LOS ANGELES -- Los Angeles police have confirmed that Pop star Michael Jackson has died at the age of 50.

Jackson was rushed to UCLA Medical Center by ambulance this afternoon after suffering from cardiac arrest, fire officials confirm.

Los Angeles Fire Department Captain Steve Ruda said paramedics responded to a 911 call at Jackson's Holmby Hills home in the 100 block of Carolwood Drive off Sunset Boulevardaround 12:26 p.m.

The 50-year old was not breathing when they arrived. The paramedics performed CPR and took him to UCLA Medical Center, Ruda says.

Jackson's mother, Katherine, arrived at UCLA around 2:30 p.m. Jackson's father, Joe, who is in Las Vegas, told reporters earlier that son was "not doing well."

His sister Latoya reportedly ran from the hospital emergency room in tears after seeing her brother.

The circumstances of Jackson's death remain unclear.

Law enforcement sources said that Los Angeles Police Department robbery-homicide detectives have opened an investigation into the death, though they stressed there is no evidence of criminal wrongdoing.

The detectives plan to interview relatives, friends and Jackson's doctors to try to figure out what happened.

The L.A. County coroner's office will determine a cause of death.

Jackson is survived by 3 children, Michael Joseph Jackson, Jr., Paris Michael Katherine Jackson and Prince "Blanket" Michael Jackson II.

Michael Jackson first gained national exposure with his brothers -- Tito, Jermaine, Jackie and Marlon -- as part of the Jackson 5. The group opened for artists such as Gladys Knight and the Pips and James Brown.

Motown Founder Berry Gordon signed the group in 1968. But as their popularity grew, some of the Jackson brothers began branching out on their own.

But it was Michael who became a sensation -- most notably with the 1979 release of the album "Off the Wall." His status as a musical superstar was cemented in 1982 after the release of "Thriller," an album that generated seven top-10 hits. While performing his hit song "Billie Jean" on a television special, Jackson showed off what would become one of his signature dance moves -- the moonwalk.

Five of his solo studio albums have become some of the world's best-selling records: Off the Wall (1979), Thriller (1982), Bad (1987), Dangerous (1991) and HIStory (1995).

Videos such as "Black or White" and "Scream" made Jackson an enduring staple on MTV in the 1990s.

He was perhaps the most exciting performer of his generation, known for his feverish, crotch-grabbing dance moves, his high-pitched voice punctuated with squeals and titters. His single sequined glove and tight, military-style jacket were trademarks second only to his ever-changing, surgically altered appearance.

Over the course of his career, however, his personal life came under more and more scrutiny, most notably an obvious change in his skin tone. In 1993, Jackson told Oprah Winfrey that the change was caused by a skin disease.

Also during that time, a 13-year-old boy claimed that Jackson had fondled him during a sleepover at the singer's 2,900-acre Neverland Ranch compound in Los Olivos, Santa Barbara County. Jackson denied any wrongdoing and eventually reached a settlement with the boy's family.

In 2005, he was tried and acquitted of lewd conduct with a minor in Santa Barbara County. After the trial, Jackson moved to Bahrain, far from the constant media scrutiny that dogged him in California.

Beset by financial difficulties, Jackson sold Neverland Ranch in 2008.

He married Lisa Marie Presley in 1994, but they divorced after only two years.

He then married a nurse named Debbie Rowe, who -- through artificial insemination -- became the mother of two of his children, Michael Joseph Jackson Jr. and Paris Michael Katherine Jackson. He had another son, Prince "Blanket" Michael Jackson II, with an unknown woman.

Jackson and Rowe divorced in 1999.