'Wild Boys of the Road' (1933)
Two middle-class teenagers quit high school and leave their families because of economic problems. They end up riding the rails, along with a girl disguised as a boy, in hopes of finding a job so they can send money back home.
The update: This time around, they are gay high school buddies who set out with their best gal pal for greener pastures in their SUV. But the grass isn't greener for them. Along the way, they are carjacked. Instead of going into a life of crime to make ends meet, the boys disguise themselves as girls and they become an all-girl musical trio.
Suggested casting: Michael Cera, Christopher Mintz-Plasse and Kat Dennings