Rivers said backup forward Matt Barnes (bruised right thigh) will not play for the third consecutive game.
Houston All-Star guard James Harden has a bruised left foot and a sore right foot and said he will be a game-time decision.
Both teams are looking for victories. The Clippers have lost two in a row entering the final matchup of this three-game trip.
The Rockets have lost two of their last three games, including a loss to the Lakers on Thursday night.