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Gracing 'Will & Grace'

Despite her vow to never act again, the performer took her acting chops to mega-sitcom "Will & Grace" in 2003 when she played a ditzy woman whose roommate ad was answered by Megan Mullally's Karen Walker. The two sparred in the episode as they fought over the same man and rent. Her charater name Liz was an homage to her long-time publicist Liz Rosenberg. Though Madonna's appearance had been highly anticipated (it was also timed to the release of her "American Life" album), her sleepy performance didn't deliver the ratings it promised and the storyline was pretty much salvaged by Mullally's performance.Chris Haston / NBC