Three Durham pitchers combined on the two-hit shutout, with Alex Colome (1-0) throwing the first six innings.
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The Richmond Flying Squirrels (4-4) dropped their third game in a row, falling 6-5 in 11 innings in the Trenton Thunder's home opener despite a late comeback.
Slade Heathcott tripled and scored on Ramon Flores' sacrifice fly to give the Thunder, the New York Yankees' Double-A affiliate, a walk-off triumph.
The Squirrels trailed 5-1 after seven innings on a chilly night but rallied for three runs in the eighth and pulled even on Adam Duvall's RBI single in the ninth.
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